Preview

Russian Journal of Geriatric Medicine

Advanced search

A Novel Functional Status-Oriented Method for Assessing Operative Risk in Older Patients Undergoing Coronary Artery Bypass Grafting

https://doi.org/10.37586/2686-8636-2-2024-133-139

Abstract

Background. Currently, there is no standardized method for assessing risk before cardiac surgery in older individuals. Recognized operative risk scales do not consider the features of older patients.

Aim. To create a scale that can forecast early postoperative outcomes after coronary artery bypass grafting in patients aged over 75 by conducting a comprehensive geriatric assessment.

Materials and methods. The study enrolled 83 patients aged 75 and older who required myocardial revascularization, with emergency surgery cases as the exclusion criteria. In addition to the standard screening, all patients underwent comprehensive geriatric assessment, including frailty screening, cognitive assessment, depression screening, grip strength, and short physical performance battery test (walking speed, sit-to-stand performance, standing balance).

Results. Six mathematical models predicting coronary artery bypass grafting outcomes were developed: duration of mechanical ventilation (р=0,012), length of stay in intensive care unit (р<0,001), duration of bed rest after surgery (р<0,001), duration of inotropic support (р<0,001), risk of acute cerebrovascular accident (р=0,015), postoperative length of stay (р=0,003). Within Microsoft Excel, mathematical models were used to devise the «Geriatric prognostic scale» for anticipating early postoperative outcomes post coronary artery bypass grafting. To estimate the risk, the following data must be entered: walking speed (m/s), grip strength (kg), sit-to-stand performance (sec), standing balance (sec), total score on the Brief Physical Functioning Test Battery, and total ejection fraction using the Simpson method (%).

Conclusion. The developed method allows for the early prediction of outcomes in coronary artery bypass grafting for patients over 75 based on functional status. This is a significant addition to traditional risk scales, which do not consider the features of older patients. The method is straightforward to implement and can be applied independently by the patient's treating physician.

About the Authors

A. V. Grishenok
Bakulev Scientific Center for Cardiovascular Surgery Russian Academy of Medical Sciences
Russian Federation

Grishenok Alena V., post-graduate student, Clinical Diagnostic Department

Moscow



V. J. Buziashvili
Bakulev Scientific Center for Cardiovascular Surgery Russian Academy of Medical Sciences
Russian Federation

Buziashvili Viktorija U., MD, PhD, Researcher, Clinical Diagnostic Department

Moscow



S. T. Matskeplishvili
Bakulev Scientific Center for Cardiovascular Surgery Russian Academy of Medical Sciences
Russian Federation

Matskeplishvili Simon Т., MD, PhD, professor, corresponding member of the Russian Academy of Sciences, Head Researcher, Clinical Diagnostic Departmen

Moscow



J. I. Buziashvili
Bakulev Scientific Center for Cardiovascular Surgery Russian Academy of Medical Sciences
Russian Federation

Buziashvili Jurij I., MD, PhD, professor, professor, academician of the Russian Academy of Sciences, Head of the Clinical Diagnostic Department

Moscow



I. V. Koksheneva
Bakulev Scientific Center for Cardiovascular Surgery Russian Academy of Medical Sciences
Russian Federation

Koksheneva Inna V., MD, PhD, Senior Researcher, Clinical Diagnostic Department

Moscow



S. L. Gvalija
Bakulev Scientific Center for Cardiovascular Surgery Russian Academy of Medical Sciences
Russian Federation

Gvalija Sof'ja L., post-graduate student, Clinical Diagnostic Department

Moscow



References

1. Barbeito A., Forman D.E. Prehabilitation: evolving role in contemporary cardiac surgery. Nat Rev Cardiol. 2023;20(12):793794. doi:10.1038/s41569-023-00939-2

2. Matsue Y., Kamiya K., Saito H., et al. Prevalence and prognostic impact of the coexistence of multiple frailty domains in elderly patients with heart failure: the FRAGILE-HF cohort study. Eur J Heart Fail. 2020;22(11):2112-2119. doi:10.1002/EJHF.1926

3. Yu J., Kong Y.G., Park J.Y., et al. Chart-Derived Frailty Index and 90-Day Mortality After Burn Surgery. Journal of Surgical Research. 2024;293:291-299. doi:10.1016/j.jss.2023.08.041

4. Gong S., Qian D., Riazi S., et al. Association Between the FRAIL Scale and Postoperative Complications in Older Surgical Patients: A Systematic Review and Meta-Analysis. Anesth Analg. 2023;136(2):251-261. doi:10.1213/ANE.0000000000006272

5. Parker S.G., Mccue P., Phelps K., et al. What is Comprehensive Geriatric Assessment (CGA)? An umbrella review. Age Ageing. 2018;47:149-155. doi:10.1093/ageing/afx166

6. Shahrokni A., Alexander K. What will perioperative geriatric assessment for older cancer patients look like in 2025? Advantages and limitations of new technologies in geriatric assessment. European Journal of Surgical Oncology. 2020;46(3):305-309. doi:10.1016/j.ejso.2019.07.026

7. O.N. Tkacheva, Yu.V. Kotovskaya, N.K. Runikhina, E.V. Frolova, A.V. Naumov, N.M. Vorobyeva, V.S. Ostapenko, E.A. Mkhitaryan, N.V. Sharashkina, E.A. Tyukhmenev, A.P. Pereverzev, E.N. Dudinskaya. CLINICAL GUIDELINES FRAILTY. Russian Journal of Geriatric Medicine. 2020; 1: 11–46. (In Russ.)] doi:10.37586/2686-8636-1-2020-11-46

8. Nashef SAM, Roques F., Sharples L.D., et al. EuroSCORE II. European Journal of Cardio-Thoracic Surgery. 2012;41(4):734745. doi:10.1093/ejcts/ezs043

9. Kaneko H., Yano Y., Okada A., et al. Age‐Dependent Association Between Modifiable Risk Factors and Incident Cardiovascular Disease. J Am Heart Assoc. 2023;12(2):27684. doi:10.1161/JAHA.122.027684

10. Fan G. Fu S., Zheng M., et al. Association of preoperative frailty with pulmonary complications after cardiac surgery in elderly individuals: a prospective cohort study. Aging Clin Exp Res. 2023;35(11):2453-2462. doi:10.1007/s40520-023-02527-3

11. Morisawa T., Saitoh M., Otsuka S., et al. Association between hospital-acquired functional decline and 2-year readmission or mortality after cardiac surgery in older patients: a multicenter, prospective cohort study. Aging Clin Exp Res. 2023;35(3):649-657. doi:10.1007/s40520-022-02335-1

12. Khadaroo R.G., Warkentin L.M., Wagg A.S., et al. Clinical Effectiveness of the Elder-Friendly Approaches to the Surgical Environment Initiative in Emergency General Surgery. JAMA Surg. 2020;155(4). doi:10.1001/jamasurg.2019.6021


Review

For citations:


Grishenok A.V., Buziashvili V.J., Matskeplishvili S.T., Buziashvili J.I., Koksheneva I.V., Gvalija S.L. A Novel Functional Status-Oriented Method for Assessing Operative Risk in Older Patients Undergoing Coronary Artery Bypass Grafting. Russian Journal of Geriatric Medicine. 2024;(2):133-139. (In Russ.) https://doi.org/10.37586/2686-8636-2-2024-133-139

Views: 433


Creative Commons License
This work is licensed under a Creative Commons BY-NC-SA 4.0.


ISSN 2686-8636 (Print)
ISSN 2686-8709 (Online)