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Метаболизм мышечной ткани у лиц пожилого возраста

https://doi.org/10.37586/2686-8636-2-2022-96-102

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Аннотация

Саркопения — генерализованное прогрессирующее заболевание скелетных мышц, которое ассоциировано с повышенным риском инвалидности и смертности вследствие падений и переломов. В статье подробно изложены современные сведения о возрастных особенностях метаболизма и ремоделирования мышечной ткани, которые приводят к развитию саркопении и её дальнейшему прогрессированию. Представлены возможности коррекции саркопении: разобран механизм действия экспериментальных лекарственных средств, действующих на мышечную ткань (миостатин, бимагрумаб, ландогрозумаб), а также доказавших эффективность немедикаментозных способов коррекции саркопении (питание, физические нагрузки), изложены возможные эффекты приёма препаратов витамина D для пациентов с саркопенией.

Об авторах

Е. В. Иванникова
ФГАОУ ВО РНИМУ им. Н.И. Пирогова Минздрава России, Российский геронтологический научно-клинический центр
Россия

Москва



Е. Н. Дудинская
ФГАОУ ВО РНИМУ им. Н.И. Пирогова Минздрава России, Российский геронтологический научно-клинический центр
Россия

Москва



Ю. С. Онучина
ФГАОУ ВО РНИМУ им. Н.И. Пирогова Минздрава России, Российский геронтологический научно-клинический центр
Россия

Москва



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Рецензия

Для цитирования:


Иванникова Е.В., Дудинская Е.Н., Онучина Ю.С. Метаболизм мышечной ткани у лиц пожилого возраста. Российский журнал гериатрической медицины. 2022;(2):96-102. https://doi.org/10.37586/2686-8636-2-2022-96-102

For citation:


Ivannikova E.V., Dudinskaya E.N., Onuchina Yu.S. Muscle metabolism in older adults. Russian Journal of Geriatric Medicine. 2022;(2):96-102. (In Russ.) https://doi.org/10.37586/2686-8636-2-2022-96-102

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