Vascular ageing in elderly patients with metabolic syndrome
https://doi.org/10.37586/2686-8636-1-2020-74-80
Abstract
Vascular aging is associated with increased arterial stiffness, vascular remodeling, and increased pulse wave propagation rate. This process can be accelerated by cumulative exposure to various factors that damage the arterial wall: arterial hypertension, hyperglycemia, dyslipidemia, smoking, etc. At present, there is no convincing evidence of the preferential effect of certain components of metabolic syndrome that have the greatest impact on the acceleration of vascular aging in older patients. In this regard, a non-interactive study was conducted to calculate vascular age and compare it with passport age in patients over 65 years of age with metabolic syndrome (MS) and obesity, assessing the greatest contribution to vascular ageing in a given age group of different MS components. The study showed that at different age periods MS components have different specific weights in the formation of early vascular aging.
About the Authors
S. V. Nedogoda
Volgograd State Medical University, Department of Therapy and Endocrinology of the Faculty of Medical Excellence
Russian Federation
Russian Federation
S.V. Nedogoda, MD, PhD, professor, Head of Internal Diseases and Endocrinology Departament
+7(8442) 97-42-51
SPIN-код: 7005-7846
V. V. Tsoma
Volgograd State Medical University, Department of Therapy and Endocrinology of the Faculty of Medical Excellence
Russian Federation
Russian Federation
V.V. Tsoma, MD, PhD, associate professor, Internal Diseases and Endocrinology Department
+7(917) 833-27-76
SPIN-код: 4918-3790
E. V. Chumachek
Volgograd State Medical University, Department of Therapy and Endocrinology of the Faculty of Medical Excellence
Russian Federation
Russian Federation
E.V. Chumachek, MD, PhD, associate professor, Internal medicine and endocrinology Departament
+7(917) 339-1384
SPIN-код: 6298-2220
V. O. Smirnova
Volgograd State Medical University, Department of Therapy and Endocrinology of the Faculty of Medical Excellence
Russian Federation
Russian Federation
V.O. Smirnova, assistant fellow, Internal Diseases and Endocrinology Departament
+7(902) 096-44-65
SPIN-код: 4601-9910
R. V. Palashkin
Volgograd State Medical University, Department of Therapy and Endocrinology of the Faculty of Medical Excellence
Russian Federation
Russian Federation
R.V. Palashkin, PhD-student, Internal Diseases and Endocrinology Departament
+7(927) 538-6971
SPIN-код: 6481-1370
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Review
For citations:
Nedogoda S.V., Tsoma V.V., Chumachek E.V., Smirnova V.O., Palashkin R.V. Vascular ageing in elderly patients with metabolic syndrome. Russian Journal of Geriatric Medicine. 2020;(1):74-80. (In Russ.) https://doi.org/10.37586/2686-8636-1-2020-74-80
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