Mixed dementia in stroke patient
https://doi.org/10.37586/2686-8636-3-2020-236-242
Abstract
The stroke is linked to the high risk of the subsequent cognitive impairment. At the same time results of longitudinal studies suggest that in many patients main factor of post-stroke cognitive impairment is neurodegenerative changes, typical for Alzheimer's disease. Relationship of vascular and neurodegenerative components of post-stroke dementia is very complex and diagnostic of co-occurring Alzheimer's disease in stroke survivors is associated with severe difficulties. Differentiation of pure vascular and mixed dementia after stroke may be critical due to the additive and synergistic effects of vascular and neurodegenerative components associated with poorer prognosis and possible differences in effectiveness and tolerability of basic anti-dementia drugs. Presented clinical case illustrates modern methods of laboratory and instrumental diagnostics that facilitates the identification of concomitant Alzheimer's disease. Correlation of non-clinic data with specific neuropsychological pattern of possible concomitant Alzheimer's disease is shown. A close relationship of cognitive and other neuropsychiatric disorders in a patient who had a stroke is noted.
About the Author
M. A. Cherdak
Pirogov Russian National Research Medical University, Faculty of Additional Professional Education, Department of Aging Diseases
Russian Federation
Russian Federation
MD, PhD, Assistant Professor of Department of aging diseases, Faculty of additional professional education, Pirogov Russian National Research Medical University.
Moscow.
+7(926)5604289
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For citations:
Cherdak M.A. Mixed dementia in stroke patient. Russian Journal of Geriatric Medicine. 2020;(3):236-242. (In Russ.) https://doi.org/10.37586/2686-8636-3-2020-236-242
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