Active longevity: long-term clinical observation
https://doi.org/10.37586/2686-8636-4-2020-339-349
Abstract
Objective. The work is aimed to analyze the biochemical and lipid blood profile of patient Z and to evaluate the effect of a long-term garlic (Allium sativum L.) — based diet on aging-associated processes and slowing down pathological processes in heart-vessels system.
Materials and methods. Blood profiles of the patient Z are studied which represents seventythree years old physically active man with intellectual professional activity who played lawn tennis twice a week for the 45 years and followed a consistent vegetarian diet without any meat and milk products (for 32 years), and a garlic-based diet for the last 11 years. The garlic diet represents uptake of one head of raw garlic every day orally (totally 25–30 g, e.g., 1 g of raw garlic per 3 kg of body weight 5–6 days a week) for 11 years. General, biochemical and lipid blood tests were examined during 15 years.
Results. Laboratory blood tests of 2003 are testified the ill-being at the level of lipid profile and heart-vessels system as a result of pathological conditions and aging. As a result of garlic intake starting from 2007, blood biochemical profile is started to testify that negative changes at the patient Z’s organism are slowed, levels of cholesterol, triglycerides, lipoproteins, creatinine and endotoxin being normalized. As a result of long-term garlic intake the stabilization of indicators of his organism systems was found: namely, the molecular and cellular blood composition, the neck and head vessels, and a high adaptive and reproductive resource of the organism.
Conclusion. After the introduction of the garlic diet in 2007, blood tests and ultrasound examinations of the body blood vessels indicate that, despite of age and refusal to take pharmaceuticals, the triglyceridemia and hypercholesterolemia diagnoses have been withdrawn; hypertension has stopped progressing, and arterial blood pressure is stabilized. It is assumed that the bioactive components of garlic exhibit bioantioxidant and geroprotective properties and enhance tissue regeneration. Thus, a garlic-based diet may be recommended to reduce the effects of environmental stressors and to slow down the aging-associated processes.
About the Authors
R. I. ZhdanovRussian Federation
PhD, DSci, Doctor of Sciences (Chemistry), Professor (Biophysics), honorary member of the Republic of Tatarstan Academy of Sciences, Professor at the AllUniversity Chair of Physical Education and Sports, Kazan (Volga region) Federal University;
Chairman of the Committee for Science and Innovations, the Interregional Clinical and Diagnostics Center, Republic of Tatarstan Ministry of Healthcare;
Chief researcher at the Russian Institute of Advanced Studies, the Moscow State Pedagogical University
Kazan
Moscow
I. M. Khabibullin
Russian Federation
MD, Chair of the Department of Cardiology № 3
Kazan
E. F. Khammatova
Russian Federation
MD, physician cardiologist, the Department of Cardiology № 3
Kazan
V. I. Aidarov
Russian Federation
MD, PhD, honorary physician of the Republic of Tatarstan, Chair of the Department of Physical Therapy
Kazan
S. I. Zhdanova
Russian Federation
MD, PhD, assistant at the Chair of Hospital Pediatry
Kazan
V. G. Dvoenosov
Russian Federation
PhD, DSci, Professor, Chair of the All-University Department of Physical Education and
Sports
Kazan
R. N. Khairullin
Russian Federation
MD, PhD, DSci, the Honor Physician of the Republic of Tatarstan, Director Genera
Kazan
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Review
For citations:
Zhdanov R.I., Khabibullin I.M., Khammatova E.F., Aidarov V.I., Zhdanova S.I., Dvoenosov V.G., Khairullin R.N. Active longevity: long-term clinical observation. Russian Journal of Geriatric Medicine. 2020;(4):339-349. (In Russ.) https://doi.org/10.37586/2686-8636-4-2020-339-349