Review of polymorphisms, associated with cardiovascular diseases
https://doi.org/10.37586/2686-8636-4-2020-333-338
Abstract
In this research we examined studies of gene polymorphisms, associated with cardiovascular diseases through renin-angiotensin-aldosterone system activation (AGT с.521С>Т, AСE Ins>Del), nitric oxide decline (NOS3 с.894G>T), chronic inflammation (TNF -238G>A, MMP9 -1562С>T) and oxidative stress (CYBA c.214Т>С).
About the Authors
A. A. Akopyan
Pirogov Russian National Research Medical University of Ministry of Health of the Russian Federation, Russian Gerontology Research and Clinical Centre
Russian Federation
Russian Federation
MD, Junior researcher, laboratory of translational gerontology
Moscow
I. D. Strazhesko
Pirogov Russian National Research Medical University of Ministry of Health of the Russian Federation, Russian Gerontology Research and Clinical Centre;
Medical Scientific and Educational Center of Lomonosov Moscow State University
Russian Federation
Russian Federation
MD, PhD, Deputy Director of translational medicine;
Leading Researcher at the Department of Agerelated diseases
Moscow
O. N. Tkacheva
Pirogov Russian National Research Medical University of Ministry of Health of the Russian Federation, Russian Gerontology Research and Clinical Centre
Russian Federation
Russian Federation
MD, PhD, professor, Director
Moscow
A. P. Yesakova
Pirogov Russian National Research Medical University of Ministry of Health of the Russian Federation, Russian Gerontology Research and Clinical Centre;
Moscow State University of Medicine and Dentistry
Russian Federation
Russian Federation
MD, Junior researcher at laboratory of translational gerontology;
Assistant of the department of medical genetics
Moscow
I. A. Orlova
Medical Scientific and Educational Center of Lomonosov Moscow State University
Russian Federation
Russian Federation
MD, PhD, Professor, Head of the Department of Age-associated diseases
Moscow
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Review
For citations:
Akopyan A.A., Strazhesko I.D., Tkacheva O.N., Yesakova A.P., Orlova I.A. Review of polymorphisms, associated with cardiovascular diseases. Russian Journal of Geriatric Medicine. 2020;(4):333-338. (In Russ.) https://doi.org/10.37586/2686-8636-4-2020-333-338
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