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Hospital Rapid Geriatric Assessment Scale — a new diagnostic tool for frailty screening

https://doi.org/10.37586/2686-8636-2-2023-111-120

Abstract

Background. The Short Physical Performance Battery (SPPB) is considered a standard screening test for frailty, however certain conditions it requires are frequently inaccessible.

Aim. To develop Hospital Rapid Geriatric Assessment Scale (HRGAS) and to evaluate its diagnostic value in frailty screening.  

Materials and methods. 408 sequentially hospitalized patients (23% male) aged 60–95 (median 73) years were examined using our specially designed algorithm (HRGAS) that includes 9 items: 1) age; 2) Mini-Cog test; 3) short depression assessment; 4) dynamometry; 5) falls in the past year; 6) mobility; 7) self-feeding ability; 8) urinary incontinence; 9) body mass index. The results were scored from 0 to 3 for age and from 0 to 2 for all other items. Minimum score sum is 0, maximum — 19. Assessment time was approximately 5 minutes. As control SPPB was used for frailty screening. The HRGAS results were compared with SPPB. 

Results. Based on SPPB, frailty rate was 46,3%, pre-frail — 26%, robust — 27,7%. HRGAS score was ranged from 0 to 14 (median 4, IQR 2–6) and negatively correlated to SPPB score (rS = -0,63; p<0,001). For frailty detection (SPPB score 0–7), ROC-analysis showed AUC 0,815 (95% CI 0,774–0,856), p<0,001, cut-off value ≥5, sensitivity 67,2%, specificity 81,3%, positive prognostic value (PPV) 76,5%, negative prognostic value (NPV) 74,2%, diagnostic accuracy 74,8%. For robust detection (SPPB score 10–12), ROC-analysis showed AUC 0,805 (95% CI 0,761–0,849), p<0,001, cut-off value ≤2, sensitivity 55,8%, specificity 84,1%, PPV 57,3%, NPV 83,2%, diagnostic accuracy 76,2%.  

Conclusion. We developed HRGAS and calculated its cut-off values to identify and rule out frailty syndrome: score 0–2 by HRGAS indicate robust, score 3–4 — pre-frail and score ≥5 — frail patients.

About the Authors

N. M. Vorobyeva
Pirogov Russian National Research Medical University, Russian Gerontology Research and Clinical Centre
Russian Federation

Vorobyeva Natalia M., MD, PhD, senior researcher, Clinical Pharmacology and Pharmacotherapy Laboratory

Moscow



I. P. Malaya
Pirogov Russian National Research Medical University, Russian Gerontology Research and Clinical Centre
Russian Federation

Malaya Irina P., MD, PhD, Head of Clinical Pharmacology and Pharmacotherapy Laboratory

Moscow



G. V. Semochkina
Pirogov Russian National Research Medical University, Russian Gerontology Research and Clinical Centre
Russian Federation

Semochkina Galina V., Acting Head Nurse

Moscow



Yu. V. Kotovskaya
Pirogov Russian National Research Medical University, Russian Gerontology Research and Clinical Centre
Russian Federation

Kotovskaya Yulia V., MD, PhD, professor, Deputy Director, Russian Gerontology Research and Clinical Centre

Moscow



N. V. Sharashkina
Pirogov Russian National Research Medical University, Russian Gerontology Research and Clinical Centre
Russian Federation

Sharashkina Natalia V., MD, PhD, Head of Geriatrics Laboratory, Associate Professor, Age-Related Diseases Department

Moscow



N. K. Runikhina
Pirogov Russian National Research Medical University, Russian Gerontology Research and Clinical Centre
Russian Federation

Runikhina Nadezhda K., MD, PhD, professor, Deputy Director

Moscow



O. N. Tkacheva
Pirogov Russian National Research Medical University, Russian Gerontology Research and Clinical Centre
Russian Federation

Tkacheva Olga N., MD, PhD, professor, corresponding member of the Russian Academy of Sciences, Director

Moscow



References

1. Tkacheva O.N., Kotovskaya Yu.V., Runikhina N.K. et  al. Clinical guidelines on  frailty. Russian Journal of Geriatric Medicine. 2020; (1): 11–46. (In Russ).

2. Tkacheva O.N., Kotovskaya Yu.V., Runikhina N.K. et  al. Clinical guidelines frailty. Part 2. Russian Journal of Geriatric Medicine. 2020; (2): 115– 130. (In Russ).

3. Guralnik J.M., Simonsick E.M., Ferrucci L. et al. A short physical performance battery assessing lower extremity function: association with self-reported disability and prediction of mortality and nursing home admission. J Gerontol, 1994; 49 (2): M85–M94. DOI: 10.1093/geronj/49.2.M85.

4. Abizanda P., Romero L., Sanchez-Jurado P.M. et  al. Association between functional assessment instruments and frailty in older adults: the FRADEA study. J Frailty Aging, 2012; 1 (4): 162– 168. DOI: 10.14283/jfa.2012.25.

5. da Camara S.M., Alvarado B.E., Guralnik J.M. et al. Using the short physical performance battery to screen for frailty in young-old adults with distinct socioeconomic conditions. Geriatr Gerontol Int, 2013; 13 (2): 421–428. DOI: 10.1111/j.1447-0594.2012.00920.x.

6. Bandinelli S., Lauretani F., Boscherini V. et  al. A  randomized, controlled trial of  disability prevention in  frail older patients screened in  primary care: the FRASI study. Design and baseline evaluation. Aging Clin Exp Res, 2006; 18 (5): 359–366. DOI: 10.1007/BF03324831.

7. Freire A.N., Guerra R.O., Alvarado B. et al. Validity and reliability of the short physical performance battery in two diverse older adult populations in Quebec and Brazil. J Aging Health, 2012; 24 (5): 863–878. DOI: 10.1177/0898264312438551.

8. Baldwin M.R., Reid M.C., Westlake A.A. et al. The feasibility of measuring frailty to predict disability and mortality in older medical intensive care unit survivors. J Crit Care, 2014; 29 (3): 401–408. DOI: 10.1016/j.jcrc.2013.12.019.

9. Egashira R., Sato T., Miyake A. et al. The Japan Frailty Scale is a promising screening test for frailty and pre-frailty in Japanese elderly people. Gene, 2022; 844: 146775. DOI: 10.1016/j.gene.2022.146775.


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For citations:


Vorobyeva N.M., Malaya I.P., Semochkina G.V., Kotovskaya Yu.V., Sharashkina N.V., Runikhina N.K., Tkacheva O.N. Hospital Rapid Geriatric Assessment Scale — a new diagnostic tool for frailty screening. Russian Journal of Geriatric Medicine. 2023;(2):111-120. (In Russ.) https://doi.org/10.37586/2686-8636-2-2023-111-120

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ISSN 2686-8636 (Print)
ISSN 2686-8709 (Online)