geriatrРоссийский журнал гериатрической медициныRussian Journal of Geriatric Medicine2686-86362686-8709Сайт издателя10.37586/2686-8636-1-2020-81-85geriatr-9Research ArticleКЛИНИЧЕСКИЕ РАЗБОРЫCLINICAL CASESПациент с кардиоваскулярной патологией и анемией: роковое сочетание или привычная закономерность?A patient with cardiovascular disease and anaemia: fatal combination or consistent pattern?https://orcid.org/0000-0002-3066-4866ХовасоваН. О.KhovasovaN. O.

Ховасова Наталья Олеговна  — канд. мед. наук, доцент кафедры болезней старения

ст. научный сотрудник лаборатории заболеваний костно-мышечной системы 

телефон: +7(915) 004-43-00

N.O. Khovasova, Md, PhD, associate professor, Age-related diseases Department

senor research fellow, Laboratory of  musculoskeletal diseases

+7(915) 004-43-00 

natashahov@mail.ruhttps://orcid.org/0000-0002-6253-621XНаумовА. В.NaumovA. V.

Наумов Антон Вячеславович — д-р мед. наук, профессор кафедры болезней старения

заведующий лабораторией заболеваний костно-мышечной системы 

телефон: +7(926) 890-40-20

A.V. Naumov, MD, PhD, professor of  Age-related diseases Departament

Head of  Laboratory of  musculoskeletal diseases

+7(926) 890-40-20

nanton78@gmail.comФДПО ФГАОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России, Российский геронтологический научно-клинический центрРоссияPirogov Russian National Research Medical University of Ministry of Health of Russian federation Russian Gerontology Research and Clinical CentreRussian Federation202022022020018185Copyright © Ховасова Н.О., Наумов А.В., 20202020Ховасова Н.О., Наумов А.В.Khovasova N.O., Naumov A.V.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.geriatr-news.com/jour/article/view/9

Анемия — распространенный клинико-лабораторный синдром, осложняющий многие соматические заболевания. Особую значимость снижение гемоглобина имеет у пациентов с сердечно-сосудистыми заболеваниями. Анемия увеличивает как частоту, так и прогноз кардиоваскулярных заболеваний. В статье приведен типичный клинический случай пожилой пациентки с хронической сердечной недостаточностью и нормоцитарной анемией, представлен алгоритм ведения и тактика лечения анемии.

Anemia is  a common clinical and laboratory syndrome, complicating many somatic diseases. Of particular importance is the reduction of hemoglobin in patients with cardiovascular diseases. Anemia increases both the frequency and prognosis of cardiovascular disease. The article presents a  typical clinical case of  an elderly patient with chronic heart failure and normocytic anemia, presents the algorithm of management and tactics of treatment of anemia.

анемиямикроцитарная анемиясывороточное железоферритинанемия хронических заболеванийхроническая сердечная недостаточностьanemiamicrocytic anemiaserumal ironferritinanemia of chronic diseaseschronic heart failureReferencesCulleton B.F., Manns B.J., Zhang J., Tonelli M., Klarenbach S., Hemmelgarn B.R. Impact of anemia on hospitalization and mortality in older adults. Blood. 2006;107(10):3841–6. DOI: 10.1182/ blood-2005-10-4308.Culleton B.F., Manns B.J., Zhang J., Tonelli M., Klarenbach S., Hemmelgarn B.R. Impact of anemia on hospitalization and mortality in older adults. Blood. 2006;107(10):3841–6. DOI: 10.1182/ blood-2005-10-4308.Hong C.H., Falvey C., Harris T.B., et al. Anemia and risk of dementia in older adults: Findings from the Health ABC study. Neurology. 2013; 81:528–533. DOI: 10.1212/WNL.0b013e31829e701d.Hong C.H., Falvey C., Harris T.B., et al. Anemia and risk of dementia in older adults: Findings from the Health ABC study. Neurology. 2013; 81:528–533. DOI: 10.1212/WNL.0b013e31829e701d.Elzen W.P., Willems J.M., Westendorp R.G., de Craen A.J., Assendelft W.J., Gussekloo J. Effect of anemia and comorbidity on functional status and mortality in old age: results from the Leiden 85- plus Study. Can Med Assoc J. 2009;181(3–4):151–7. DOI:10.1503/cmaj.090040.Elzen W.P., Willems J.M., Westendorp R.G., de Craen A.J., Assendelft W.J., Gussekloo J. Effect of anemia and comorbidity on functional status and mortality in old age: results from the Leiden 85- plus Study. Can Med Assoc J. 2009;181(3–4):151–7. DOI:10.1503/cmaj.090040.Eisenstaedt R., Penninx B.W., Woodman R.C. Anemia in the elderly: current understanding andemerging concepts. Blood Rev. 2006; 20(4): 213–26.Eisenstaedt R., Penninx B.W., Woodman R.C. Anemia in the elderly: current understanding andemerging concepts. Blood Rev. 2006; 20(4): 213–26.Beghe C, Wilson A., Ershler W.B. Prevalence and outcomes of anemia in geriatrics: a systematic review of the literature. Am J Med. 2004;116(Suppl 7A):3S–10S. DOI: 10.1016/j.amjmed.2003.12.009Beghe C, Wilson A., Ershler W.B. Prevalence and outcomes of anemia in geriatrics: a systematic review of the literature. Am J Med. 2004;116(Suppl 7A):3S–10S. DOI: 10.1016/j.amjmed.2003.12.009Han S.V., Park M., Kwon Y.M., Yoon H.J., Chang Y., Kim H., Lim Y.H., Kim S.G., Ko A. et al. Mild Anemia and Risk for All-Cause, Cardiovascular and Cancer Deaths in Apparently Healthy Elderly Koreans. Korean Journal of Family Medicine. 40. 10.4082/ kjfm.17.0089. DOI: 10.4082/kjfm.17.0089Han S.V., Park M., Kwon Y.M., Yoon H.J., Chang Y., Kim H., Lim Y.H., Kim S.G., Ko A. et al. Mild Anemia and Risk for All-Cause, Cardiovascular and Cancer Deaths in Apparently Healthy Elderly Koreans. Korean Journal of Family Medicine. 40. 10.4082/ kjfm.17.0089. DOI: 10.4082/kjfm.17.0089Gerards A. Winkler. M. Jokisch, S. Tebrügge, K.-H. Jöckel, R. Erbel, S. Moebus, C. Weimar. Cognitive performance and subjective cognitive decline: data from the Heinz Nixdorf recall study. Alzheimer's and Dementia 13(7):P1333 July 2017 DOI: 10.1016/j. jalz.2017.06.2050Gerards A. Winkler. M. Jokisch, S. Tebrügge, K.-H. Jöckel, R. Erbel, S. Moebus, C. Weimar. Cognitive performance and subjective cognitive decline: data from the Heinz Nixdorf recall study. Alzheimer's and Dementia 13(7):P1333 July 2017 DOI: 10.1016/j. jalz.2017.06.2050Negi P.C., Dev M., Paul P., Pal Singh D., Rathoure S., Kumar R. Prevalence, risk factors, and significance of iron deficiency and anemia in nonischemic heart failure patients with reduced ejection fraction from a Himachal Pradesh heart failure registry. Indian Heart J. 2018 Dec;70 Suppl 3:S182–S188. Epub 2018 Nov 2. DOI:10.1016/j. ihj.2018.10.032Negi P.C., Dev M., Paul P., Pal Singh D., Rathoure S., Kumar R. Prevalence, risk factors, and significance of iron deficiency and anemia in nonischemic heart failure patients with reduced ejection fraction from a Himachal Pradesh heart failure registry. Indian Heart J. 2018 Dec;70 Suppl 3:S182–S188. Epub 2018 Nov 2. DOI:10.1016/j. ihj.2018.10.032Ponikowski et al. Iron i.v. in heart failure: ready for implementation? European Heart Journal 2015 36:657-68. DOI: 10.1093/eurheartj/ehu392Ponikowski et al. Iron i.v. in heart failure: ready for implementation? European Heart Journal 2015 36:657-68. DOI: 10.1093/eurheartj/ehu392Albaramki J., Hodson E.M., Craig J.C., Webster AC. Parenteral versus oral iron therapy for adults and children with chronic kidney disease. Cochrane Database Syst Rev. 2012 Jan 18;1:CD007857. DOI:10.1002/14651858.CD007857.pub2.Albaramki J., Hodson E.M., Craig J.C., Webster AC. Parenteral versus oral iron therapy for adults and children with chronic kidney disease. Cochrane Database Syst Rev. 2012 Jan 18;1:CD007857. DOI:10.1002/14651858.CD007857.pub2.Naito Y., Tsujino T., Matsumoto M. et al. Adaptive response of the heart to long-term anemia induced by iron deficiency. American journal of physiology. Heart and circulatory physiology. 296. H585–93. 10.1152/ajpheart.00463.2008. DOI: 10.1152/ajpheart.00463.2008Naito Y., Tsujino T., Matsumoto M. et al. Adaptive response of the heart to long-term anemia induced by iron deficiency. American journal of physiology. Heart and circulatory physiology. 296. H585–93. 10.1152/ajpheart.00463.2008. DOI: 10.1152/ajpheart.00463.2008

The authors declare that there are no conflicts of interest present.