geriatrРоссийский журнал гериатрической медициныRussian Journal of Geriatric Medicine2686-86362686-8709Сайт издателя10.37586/2686-8636-2-2026-157-163geriatr-732Research ArticleОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯORIGINAL STUDIESСнижение функциональной способности мышц как ключевой маркер возраст-ассоциированных изменений мышечной тканиLoss of muscle function as the main indicator of age-related alterations in muscle tissuehttps://orcid.org/0000-0002-0789-1673УруноваГ. Р.UrunovaG. R.

Урунова Гозель Рустамовна

Москва

Urunova Gozel Rustamovna

Moscow

urunova_gr@rgnkc.ruhttps://orcid.org/0000-0002-9837-4224ДеменокД. В.DemenokD. V.

Москва

Moscow

demenok_dv@rgnkc.ruhttps://orcid.org/0000-0002-6465-4842ШарашкинаН. В.SharashkinaN. V.

Москва

Moscow

sharashkina_nv@rgnkc.ruhttps://orcid.org/0000-0002-6253-621XНаумовА. В.NaumovA. V.

Москва

Moscow

https://orcid.org/0000-0002-3066-4866ХовасоваН. О.KhovasovaN. O.

Москва

Moscow

khovasova_no@rgnkc.ruФГАОУ ВО РНИМУ им. Н. И. Пирогова Минздрава России (Пироговский Университет)РоссияPirogov Russian National Research Medical University (Pirogov Medical University), Ministry of Health of the Russian FederationRussian Federation20262504202602157163Copyright © Урунова Г.Р., Деменок Д.В., Шарашкина Н.В., Наумов А.В., Ховасова Н.О., 20262026Урунова Г.Р., Деменок Д.В., Шарашкина Н.В., Наумов А.В., Ховасова Н.О.Urunova G.R., Demenok D.V., Sharashkina N.V., Naumov A.V., Khovasova N.O.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.geriatr-news.com/jour/article/view/732

Возраст-ассоциированные изменения мышечной системы традиционно оцениваются через показатели силы (динапения) и массы (саркопения). Однако наш опыт свидетельствует о том, что наиболее значимым фактором для качества жизни гериатрических пациентов является снижение функциональной способности мышц. В данной статье предложено определение «эргопения» — снижение функциональной способности мышц при сохранной силе и/или массе мышечной ткани; представлен анализ патофизиологических механизмов, лежащих в основе снижения мышечной функции; рассмотрено их клиническое значение; а также описаны диагностические подходы. Эти подходы сопоставлены со стандартизированными методами оценки мышечной силы и мышечной массы.

Age-associated changes in the muscular system are traditionally assessed through indicators of strength (dynapenia) and mass (sarcopenia). However, clinical experience suggests that the most significant factor for the quality of life of geriatric patients is the decline in muscle functional capacity. This article proposes defining this condition as ergopenia, i.e., a reduction in muscle functional capacity in the presence of preserved muscle strength and/or mass. It presents an analysis of the pathophysiological mechanisms underlying the decline in muscle function, examines their clinical significance, and describes diagnostic approaches. These approaches are compared with standardized methods for assessing muscle strength and muscle mass.

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The authors declare that there are no conflicts of interest present.