geriatrРоссийский журнал гериатрической медициныRussian Journal of Geriatric Medicine2686-86362686-8709Сайт издателя10.37586/2686-8636-3-2020-199-204geriatr-56Research ArticleОБЗОРЫREVIEWSСовременные аспекты диагностики и лечения синдрома умеренных когнитивных расстройствModern aspects of diagnosis and treatment of mild cognitive impairmenthttps://orcid.org/0000-0001-9467-6244ЛокшинаА. Б.LokshinaA. B.

Локшина Анастасия Борисовна - ассистент кафедры нервных болезней и нейрохирургии Института клинической медицины им. Н.В. Склифосовского ФГАОУ ВО Первый МГМУ им. И.М. Сеченова Минздрава России (Сеченовский университет); ФГАОУ ВО РНИМУ им. Н.И. Пирогова Минздрава России, Российский геронтологический научно-клинический центр.

Москва.

Тел. +7(916) 243-00-28

Assistant to the Department of Nervous Diseases and Neurosurgery, Institute of Clinical Medicine named after N.V. Sklifosovsky Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Healthcare of the Russian Federation (Sechenovskiy University); Pirogov National Research Medical University, Russian Gerontology Research and Clinical Centre.

Moscow.

+7(916) 243-00-28

aloksh@mail.ruПервый МГМУ им. И.М. Сеченова (Сеченовский университет); РНИМУ им. Н.И. Пирогова Минздрава России, Российский геронтологический научно-клинический центрРоссияFederal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Healthcare of the Russian Federation (Sechenovskiy University); Pirogov Russian National Research Medical University of Ministry of Health of the Russian Federation, Russian Gerontology Research and Clinical CentreRussian Federation20200209202003199204Copyright © Локшина А.Б., 20202020Локшина А.Б.Lokshina A.B.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.geriatr-news.com/jour/article/view/56

Изучение когнитивных расстройств (КР) началось с более тяжелых форм — деменции, которая, как правило, является результатом достаточно долго протекающего патологического процесса. Ей предшествуют недементные когнитивные нарушения (включая синдром умеренных когнитивных расстройств — УКР), раннее выявление которых расширяет потенциальные возможности терапевтического воздействия и даже предотвращения дезадаптации в результате деменции. В статье проведен обзор современных публикаций по проблеме УКР. Особое внимание уделено вопросам диагностики и лечения этого клинически гетерогенного синдрома. Рассмотрены исторические вопросы изучения данного синдрома, приведены современные принципы его классификации и критерии диагностики, а также описаны основные аспекты ведения пациентов. Описаны результаты целого ряда российских и международных исследований синдрома УКР, в том числе проведено сравнение данных.

The study of cognitive impairments (CI) began with a more severe form- dementia, which is usually the result of a long-running pathological process. It is preceded by non-demented cognitive disorders (including mild cognitive impairment syndrome — MCI), whose early detection increases the potential for therapeutic effects and even prevention of disadaptation as a result of dementia. The article reviews current publications on the problem of MCI. Special attention is paid to the diagnosis and treatment of this clinically heterogeneous syndrome. Historical issues of MCI studying are considered, modern principles of its classification and diagnostic criteria are given, and the main aspects of patient management are described. The results of a number of russian and international studies of MCI syndrome are described, including a comparison of these data among themselves.

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The authors declare that there are no conflicts of interest present.