geriatrРоссийский журнал гериатрической медициныRussian Journal of Geriatric Medicine2686-86362686-8709Сайт издателя10.37586/2686-8636-2-2024-117-123geriatr-414Research ArticleОБЗОРЫREVIEWSМРТ-признаки поражения головного мозга при артериальной гипертензииMRI Signs of Brain Damage in Arterial Hypertensionhttps://orcid.org/0000-0002-8939-0716ИсайкинаО. Ю.IsaykinaO. Yu.

Исайкина Олеся Юрьевна, канд. мед. наук, ведущий научный сотрудник лаборатории применения амбулаторных диагностических методов в профилактике хронических неинфекционных заболеваний в системе здравоохранения

Москва

Isaykina Olesya Yu., MD, PhD, Lead Researcher, Laboratory for the Use of Outpatient Diagnostic Methods in the Prevention of Chronic Non-Communicable Diseases in the Health System

Moscow

oisaykina@gnicpm.ruhttps://orcid.org/0000-0003-0900-4721ВеховаК. А.VekhovaK. A.

Вехова Ксения Андреевна, студент Института клинической медицины им. Н. В. Склифосовского

Москва

Vekhova Ksenia A., student, N. V. Sklifosovsky Institute of Clinical Medicine

Moscow

vka2002@bk.ruhttps://orcid.org/0009-0003-4173-0165СуховольскаяА. С.SukhovolskayaA. S.

Суховольская Анастасия Сергеевна, студент

Новосибирск

Sukhovolskaya Anastasia S., student

Novosibirsk

a.sukhovolskaya@g.nsu.ruhttps://orcid.org/0000-0003-2143-1806ЧерноусовП. А.ChernousovP. A.

Черноусов Павел Андреевич, аспирант кафедры нервных болезней и нейрохирургии Института клинической медицины им. Н. В. Склифосовского

Москва

Chernousov Pavel A., postgraduate, Department of Nervous Diseases and Neurosurgery

Moscow

pavelchernousov85@gmail.comhttps://orcid.org/0000-0002-1951-930XПерепеловаЕ. М.PerepelovaE. M.

Перепелова Елена Михайловна, канд. мед. наук, заведующая Отделением лучевой диагностики Клиники нервных болезней им. А. Я. Кожевникова

Москва

Perepelova Elena M., MD, PhD, Head of the Department of Radiology, Department of Nervous Diseases and Neurosurgery of the A.Ya. Kozhevnikov Clinic

Moscow

elena_perepelova@mail.ruhttps://orcid.org/0000-0001-5195-8997ГорбуновВ. М.GorbunovM. V.

Горбунов Владимир Михайлович, д-р мед. наук, профессор, руководитель лаборатории амбулаторных диагностических методов в профилактике хронических неинфекционных заболеваний

Москва

Gorbunov Vladimir M., MD, PhD, Head of the Laboratory for the Use of Outpatient Diagnostic Methods in the Prevention of Chronic Non-Communicable Diseases in the Health System

Moscow

vmgorbunov@gmail.comФГБУ «Национальный медицинский исследовательский центр терапии и профилактической медицины» Минздрава РоссииРоссияNational Medical Research Center for Therapy and Preventive Medicine of the Ministry of Health of the Russian FederationRussian FederationФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет)РоссияI.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)Russian FederationФГАОУ ВО «Новосибирский государственный университет»РоссияNovosibirsk State UniversityRussian Federation20243006202402117123Copyright © Исайкина О.Ю., Вехова К.А., Суховольская А.С., Черноусов П.А., Перепелова Е.М., Горбунов В.М., 20242024Исайкина О.Ю., Вехова К.А., Суховольская А.С., Черноусов П.А., Перепелова Е.М., Горбунов В.М.Isaykina O.Y., Vekhova K.A., Sukhovolskaya A.S., Chernousov P.A., Perepelova E.M., Gorbunov M.V.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.geriatr-news.com/jour/article/view/414

Представлен обзор литературы о сосудистых изменениях в головном мозге при артериальной гипертензии, регистрируемых с помощью магнитно-резонансной томографии (МРТ). К ним относятся гиперинтенсивные изменения белого вещества (ГИБВ), лакунарные инфаркты, церебральные микрокровоизлияния, расширение периваскулярных пространств и атрофические изменения отделов ГМ. Микроструктурные изменения проводящих путей белого вещества головного мозга появляются до ГИБВ и могут быть оценены с помощью диффузионновзвешенной МРТ (ДВ МРТ). Один из оцениваемых при этом параметров — коэффициент фракционной анизотропии (ФА) — служит предиктором поражения белого вещества на ранних стадиях АГ.

This paper reviews the data on cerebrovascular changes in arterial hypertension obtained by magnetic resonance imaging (MRI). These include white matter hyperintensities (WMH), lacunar infarcts, cerebral microbleeds, enlarged perivascular spaces, and brain atrophy. Microstructural white matter changes precede WMH, and can be detected using diffusion tensor MRI (DTI), which allows the analysis of fractional anisotropy (FA), indicating white matter lesions in the early stages of hypertension.

артериальная гипертензиямагнитно-резонансная томографиягиперинтенсивные изменения белого веществалакунарные инфарктыцеребральные микрокровоизлияниярасширение периваскулярных пространстватрофия головного мозгаarterial hypertensionmagnetic resonance imagingwhite matter hyperintensitylacunar infarctscerebral microbleedsenlarged perivascular spacesbrain atrophyReferencesБаланова Ю.А., Шальнова С.А., Куценко В.А., Имаева А.Э., Капустина А.В., Муромцева Г.А., Евстифеева С.Е., Максимов С.А., Бойцов С.А., Драпкина О.М. от имени участников исследования ЭССЕ-РФ. Популяционные аспекты терапии артериальной гипертензии. Фокус на фиксированные комбинации. // Артериальная гипертензия. — 2022. — Т. 28. — № 5. — С. 482–491.https://doi.org/10.18705/1607-419X-2022-28-5-482-491Balanova J.A., Shalnova S.A., Kutsenko V.A., Imaeva A.E., Kapustina A.V., Muromtseva G.A., Evstifeeva S.E., Maksimov S.A., Boytsov S.A., Drapkina O.M. Population aspects of arterial hypertension therapy. 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The authors declare that there are no conflicts of interest present.