geriatrРоссийский журнал гериатрической медициныRussian Journal of Geriatric Medicine2686-86362686-8709Сайт издателя10.37586/2686-8636-1-2024-30-39geriatr-389Research ArticleОБЗОРЫREVIEWSФакторы риска и неблагоприятные исходы гипогликемии у пожилых больных сахарным диабетом 2 типа (обзор литературы)Risk factors and adverse outcomes of hypoglycemia in older patients with type 2 diabetes mellitus (review)https://orcid.org/0000-0003-0027-1786БулгаковаС. В.BulgakovaS. V.

Булгакова Светлана Викторовна , д-р мед. наук, доцент, заведующая кафедрой эндокринологии и гериатрии

Самара

Bulgakova Svetlana V., MD, PhD, professor, Head of the Department of Endocrinology and Geriatrics

Samara

geriatry@mail.ruhttps://orcid.org/0009-0004-6243-6528МерзловаП. Я.MerzlovaP. Ya.

Мерзлова Полина Ярославовна, ассистент кафедры эндокринологии и гериатрии

Самара

Merzlova Polina Y., MD, assistant professor, the Department of Endocrinology and Geriatrics

Samara

p.ya.merzlova@samsmu.ruhttps://orcid.org/0000-0003-4114-5233КурмаевД. П.KurmaevD. P.

Курмаев Дмитрий Петрович, канд. мед. наук, ассистент кафедры эндокринологии и гериатрии

Самара

Kurmaev Dmitry P., MD, PhD, assistant professor in Endocrinology and Geriatrics Department

Samara

geriatry@mail.ruhttps://orcid.org/0000-0003-0097-7252ТреневаЕ. В.TrenevaE. V.

Тренева Екатерина Вячеславовна , канд. мед. наук, доцент кафедры эндокринологии и гериатрии

Самара

Treneva Ekaterina V. , MD, PhD, associate professor, Department of Endocrinology and Geriatrics

Samara

eka1006@yandex.ruФГБОУ ВО  «Самарский государственный медицинский университет» Минздрава РоссииРоссияSamara State Medical UniversityRussian Federation202430032024013039Copyright © Булгакова С.В., Мерзлова П.Я., Курмаев Д.П., Тренева Е.В., 20242024Булгакова С.В., Мерзлова П.Я., Курмаев Д.П., Тренева Е.В.Bulgakova S.V., Merzlova P.Y., Kurmaev D.P., Treneva E.V.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.geriatr-news.com/jour/article/view/389

В настоящее время в мире наблюдается неуклонный рост численности больных сахарным диабетом 2 типа (СД2), и  данное заболевание признано глобальной медико-социальной проблемой XXI века. Также отмечена тенденция к увеличению продолжительности жизни и, как результат, старению населения. Соответственно, возрастает количество пожилых пациентов с  СД2. Среди данной категории пациентов достаточно часто встречается гипогликемия — серьезное осложнение СД2. Гипогликемия приводит к ухудшению гликемического контроля, когнитивному дефициту и  увеличению риска неблагоприятных сердечно-сосудистых исходов у  пожилых пациентов. В  данном обзоре литературы рассмотрены факторы риска гипогликемических состояний, которые необходимо учитывать при назначении сахароснижающей терапии пациентам старшего возраста, и их прогностическая значимость в оценке риска гипогликемии. Описаны возможные негативные последствия гипогликемии и подчеркну та важность индивидуальных целей контроля гликемии у пожилых пациентов.

Currently, the world is experiencing a steady increase in the number of patients with type 2 diabetes mellitus (T2DM); this disease is recognized as a global medical and social problem of the 21st century. There is also a trend towards increasing life expectancy and, as a result, an aging population. Accordingly, the number of older patients with T2DM is increasing. Hypoglycemia, a  serious complication of  T2DM, is  quite common among this category of  patients. Hypoglycemia leads to worsening glycemic control, cognitive deficits, and an increased risk of adverse cardiovascular outcomes in older patients. This review examines the risk factors for hypoglycemic conditions that must be  taken into account when prescribing glucose-lowering therapy to  older patients and their prognostic significance in  assessing the risk of  hypoglycemia. The possible negative consequences of hypoglycemia are described and the importance of individual goals for glycemic control in older patients is emphasized.

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The authors declare that there are no conflicts of interest present.