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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">geriatr</journal-id><journal-title-group><journal-title xml:lang="ru">Российский журнал гериатрической медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Geriatric Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2686-8636</issn><issn pub-type="epub">2686-8709</issn><publisher><publisher-name>Сайт издателя</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.37586/2686-8636-2-2020-131-137</article-id><article-id custom-type="elpub" pub-id-type="custom">geriatr-33</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Распространенность синдрома старческой астении и его взаимосвязь с хроническими неинфекционными заболеваниями у пациентов амбулаторно-поликлинических учреждений г. Москвы</article-title><trans-title-group xml:lang="en"><trans-title>Prevalence of frailty and its correlation with chronic non-infectious diseases among outpatients in Moscow</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1222-3351</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Остапенко</surname><given-names>В. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Ostapenko</surname><given-names>V. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Остапенко Валентина Сергеевна, канд. мед. наук, врач-гериатр, заведующая отделением гериатрической терапии</p><p>телефон: +7(916) 244-59-24</p><p>Москва</p></bio><bio xml:lang="en"><p>MD, PhD, Head of geriatrics department</p><p>+7(916) 244-59-24</p><p>Moscow</p></bio><email xlink:type="simple">ostapenkovalent@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5272-0454</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рунихина</surname><given-names>Н. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Runikhina</surname><given-names>N. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Рунихина Надежда Константиновна, д-р мед. наук, заместитель директора по гериатрической работе</p><p>телефон: +7(499) 187-78-09</p><p>Москва</p></bio><bio xml:lang="en"><p>MD, PhD, Deputy Director</p><p>+7(499) 187-78-09</p><p>Moscow</p></bio><email xlink:type="simple">nkrunihina@rgnkc.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6465-4842</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шарашкина</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sharashkina</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шарашкина Наталья Викторовна, канд. мед. наук, с.н.с. лаборатории общей гериатрии и нейрогериатрии</p><p>телефон: +7(903) 244-27-50</p><p>Москва</p></bio><bio xml:lang="en"><p>MD, PhD, head of Geriatricas and neurogeriatrics laboratory</p><p>+7(903) 244-27-50</p><p>Moscow</p></bio><email xlink:type="simple">sharashkina_nv@rgnkc.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ФГАОУ ВО РНИМУ им. Н.И. Пирогова Минздрава России, Российский геронтологический научно-клинический центр<country>Россия</country></aff><aff xml:lang="en">Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation, Russian Gerontology Research and Clinical Centre<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>25</day><month>05</month><year>2020</year></pub-date><volume>0</volume><issue>2</issue><fpage>131</fpage><lpage>137</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Остапенко В.С., Рунихина Н.К., Шарашкина Н.В., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Остапенко В.С., Рунихина Н.К., Шарашкина Н.В.</copyright-holder><copyright-holder xml:lang="en">Ostapenko V.S., Runikhina N.K., Sharashkina N.V.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.geriatr-news.com/jour/article/view/33">https://www.geriatr-news.com/jour/article/view/33</self-uri><abstract><p>Цель исследования – изучение распространенности синдрома старческой астении (СА) и преастении, а также их взаимосвязи с хроническими неинфекционными заболеваниями (ХНИЗ) у пациентов 65 лет и старше амбулаторно-поликлинических учреждений г. Москвы.</p><sec><title>Материалы и методы</title><p>Материалы и методы. В исследование вошли 356 пациентов ≥ 65 лет (средний возраст 74,9±6,1 года), доля женщин – 80,4% (n=286). Для выявления СА использовались фенотипическая модель и модель накопления дефицитов. Наличие ХНИЗ выявлялось путем сбора анамнеза и оценки медицинской документации.</p></sec><sec><title>Результаты</title><p>Результаты. Синдром СА и преастения по критериям фенотипической модели были выявлены в 8,9% и 61,3% случаев; по критериям модели накопления дефицитов – в 4,2% и 45,8% случаев, соответственно. Среднее количество изучаемых ХНИЗ оказалось достоверно выше у пациентов со СА, диагностированной как по модели фенотипа (4,0±1,3 против 2,8±1,4), так и по модели накопления дефицитов (5,8±0,9 против 2,5±1,2). С учетом влияния возраста, риск развития преастении по критериям фенотипической модели повышается в 2,7 раза при наличии хронической сердечной недостаточности (ХСН); по критериям модели накопления дефицитов – в 5,6 раза при наличии ишемической болезни сердца (ИБС), в 4,2 раза при наличии заболеваний суставов, в 3,7 раза при наличии сахарного диабета (СД) и в 3 раза при наличии онкологического заболевания.</p></sec><sec><title>Заключение</title><p>Заключение. Выявлена высокая распространенность преастении среди пациентов амбулаторно-поликлинических учреждений г. Москвы 65 лет и старше, а также достоверная взаимосвязь СА и преастении как с общим количеством, так и с отдельными ХНИЗ. Важно проведение мероприятий по профилактике развития и прогрессирования СА среди пациентов, обращающихся за амбулаторно-поликлинической помощью и имеющих потенциально высокую распространенность ХНИЗ.</p></sec></abstract><trans-abstract xml:lang="en"><p>The aim of this study was to research the prevalence of frailty and prefrailty and their relationship with chronic non-infectious diseases among outpatients in Moscow.</p><sec><title>Methods</title><p>Methods. The study included 356 patients ≥65 years (mean age 74.9 ± 6.1), 80.4% (n = 286) were women. For identify frailty, the phenotype model and the deficit accumulation model were used. The chronic non-infectious diseases was detected by an anamnesis and evaluating medical records.</p></sec><sec><title>Results</title><p>Results. Frailty and prefrailty according to the criteria of the phenotypic model were identified in 8.9% and 61.3% cases; according to the criteria of the deficit accumulation model – in 4.2% and 45.8% cases, resp. The average number of chronic non-infectious diseases was significantly higher in patients with frailty both  – by the phenotype model (4.0 ± 1.3 vs 2.8 ± 1.4) and by the deficit accumulation model (5.8 ± 0.9 vs 2.5 ± 1.2). Taking into account the influence of age, the risk of prefrailty according to the phenotypic model increases 2.7 times in the presence of chronic heart failure; according to the deficit accumulation model – 5.6 times in the presence of coronary heart disease, 4.2 times with in the joint diseases, 3.7 times with diabetes and 3 times with cancer.</p></sec><sec><title>Conclusion</title><p>Conclusion. А high prevalence of prefrailty among outpatients in Moscow 65 years and older, as well as a reliable relationship between frailty and prefrailty with the total number and individual chronic non-infectious diseases were revealed. It is important to take measures to prevent the development and progression of frailty among outpatients, having a potentially high prevalence of chronic non-infectious diseases.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>синдром старческой астении</kwd><kwd>преастения</kwd><kwd>гериатрический синдром</kwd><kwd>хронические неинфекционные заболевания</kwd><kwd>пожилой возраст</kwd><kwd>старческий возраст</kwd></kwd-group><kwd-group xml:lang="en"><kwd>frailty</kwd><kwd>prefrailty</kwd><kwd>geriatric syndrome</kwd><kwd>chronic non-infectious diseases</kwd><kwd>elderly</kwd><kwd>old age</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Clegg A. Frailty in elderly people. Lancet. 2013; 381(9868): 752–762.</mixed-citation><mixed-citation xml:lang="en">Clegg A. Frailty in elderly people. 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