geriatrРоссийский журнал гериатрической медициныRussian Journal of Geriatric Medicine2686-86362686-8709Сайт издателя10.37586/2686-8636-3-2021-319-331geriatr-197Research ArticleОБЗОРЫREVIEWSОсобенности лечения воспалительных ревматических заболеваний у пожилыхFeatures of inflammatory rheumatic diseases treatment in older peoplehttps://orcid.org/0000-0002-5187-0108МешковА. Д.MeshkovA. D.

Москва

Moscow

https://orcid.org/0000-0003-1222-3351ОстапенкоВ. С.OstapenkoV. S.

Остапенко Валентина Сергеевна, к.м.н., доцент кафедры болезней старения, научный сотрудник лаборатории общей гериатрии ОСП

Москва

Ostapenko Valentina Sergeevna, PhD, Associate professor Department of Aging Diseases, Federal State-Funded Educational Institution of Higher Learning

Moscow

ФГАОУ ВО РНИМУ им. Н.И. Пирогова Минздрава России, Российский геронтологический научно-клинический центрРоссияPirogov Russian National Research Medical University of Ministry of Health of the Russian Federation, Russian Gerontology Research and Clinical CentreRussian Federation20211410202103327339Copyright © Мешков А.Д., Остапенко В.С., 20212021Мешков А.Д., Остапенко В.С.Meshkov A.D., Ostapenko V.S.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.geriatr-news.com/jour/article/view/197

В настоящее время увеличивается число пожилых людей с хроническими ревматическими заболеваниями. Отличительными особенностями данной популяции являются повышенный риск сердечно-сосудистых, опухолевых, инфекционных заболеваний, а также ятрогенных осложнений, при этом данная группа пациентов достаточно гетерогенна. Современные биологические и таргетные синтетические препараты, с одной стороны, дают новые, ранее недоступные, возможности лечения, с другой стороны, их использование сопряжено с риском побочных эффектов. В данном обзоре рассматриваются особенности назначения иммуносупрессивных препаратов у пожилых пациентов с ревматоидным артритом и спондилоартритами. Основой эффективного и безопасного подхода к использованию данных препаратов у пожилых может быть комплексный междисциплинарный подход с учетом гериатрических особенностей пациентов.

Currently the number of older people with chronic rheumatic diseases is increasing. Distinctive features of this population are the increased risk of cardiovascular and infectious diseases, tumours, as well as iatrogenic complications, while this group of patients is rather heterogeneous. On the one hand, modern biological and targeted synthetic drugs, provide new, previously inaccessible, treatment options; on the other hand, their use is associated with risk of side effects. In this review specifics of prescribing immunosuppressive drugs in older patients with rheumatoid arthritis and spondyloarthritis has been analyzed. An effective and safe approach to the use of these drugs in older people can be based on a comprehensive interdisciplinary approach, taking into account geriatric characteristics of the patients.

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The authors declare that there are no conflicts of interest present.