geriatrРоссийский журнал гериатрической медициныRussian Journal of Geriatric Medicine2686-86362686-8709Сайт издателя10.37586/2686-8636-2-2021-231-236geriatr-172Research ArticleВ ПОМОЩЬ ПРАКТИЧЕСКОМУ ВРАЧУTIPS FOR CLINICIANSСердечно-сосудистая коморбидность остеоартрита: клиническое значение и стратегии терапииCardiovascular comorbidity of osteoarthritis: clinical significance and therapy strategieshttps://orcid.org/0000-0002-6253-621XНаумовА. В.NaumovA. V.

Наумов Антон Вячеславович - доктор медицинских наук, профессор кафедры болезней старения ФДПО РНИМУ им. Н.И. Пирогова Минздрава России, заведующий лабораторией заболеваний костно-мышечной системы РНИМУ им. Н.И. Пирогова Минздрава России, Российский геронтологический научно-клинический центр.

Москва.

Naumov Anton V. - MD, PhD, Head of bone and muscular diseases laboratory, Pirogov National Research Medical University, Russian Gerontology Research and Clinical Centre.

Moscow.

naumov_av@rgnkc.ruРНИМУ им. Н. И. Пирогова Минздрава России, Российский геронтологический научно-клинический центрРоссияPirogov Russian National Research Medical, Russian Gerontology Research and Clinical CentreRussian Federation20210108202102241246Copyright © Наумов А.В., 20212021Наумов А.В.Naumov A.V.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.geriatr-news.com/jour/article/view/172

Коморбидность остеоартрита и сердечно-сосудистых заболеваний является наиболее частой и типичной полиморбидностью пациентов старших возрастных групп. Идентичность факторов риска, патогенетическое влияние системного воспаления низкой интенсивности, дислипидемии определяют большую степень прогрессирования и остеоартрита, и сердечно-сосудистых заболеваний у пациентов с их сочетанием. Наблюдается существенное снижение физического функционирования и потери автономности. У пациентов с остеоартритом отмечается более высокий риск сердечно-сосудистой смертности. Только комплексные программы, включающие физическую реабилитацию, нутрицевтическую поддержку и фармацевтические субстанции хондроитина сульфата и глюкозамина сульфата, могут быть эффективными и безопасными у пациентов с остеоартритом и кардиоваскулярными заболеваниями.

The comorbidity of osteoarthritis and cardiovascular disease is the most frequent and typical polymorbidity in older patients. The identity of risk factors, low intensity pathogenetic effect of systemic inflammation, dyslipidemia define a greater degree and progression of both osteoarthritis and cardiovascular diseases in patients with a combination thereof. There is a significant decline in physical functioning and loss of autonomy. There is a higher risk of cardiovascular mortality in osteoarthritis patients. Only comprehensive programs involving physical rehabilitation, nutraceutical support, and pharmaceutical substances of chondroitin sulfate and glucosamine sulfate can supply effective and safe treatment in patients with osteoarthritis and cardiovascular disease.

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The authors declare that there are no conflicts of interest present.