geriatrРоссийский журнал гериатрической медициныRussian Journal of Geriatric Medicine2686-86362686-8709Сайт издателя10.37586/2686-8636-1-2021-60-64geriatr-118Research ArticleОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯORIGINAL STUDIESIntelligenceGym — эффективный инструмент для улучшения когнитивных способностей у пожилых людейIntelligenceGym — is an effective tool to improve cognitive functions in the elderlyhttps://orcid.org/0000-0003-3347-0984ТрушковаНина ВладимировнаTrushkovaNina V.

Президент Ассоциации «Европа», Априлия, Италия. Руководитель центра когнитивного образования и моторики, Лондон, Великобритания

Master's Degree. President of the Association «Europa», Aprilia, Italy. Head of Cognitive and Motor Education Center, London, Uk.

ninaglobal2000@yahoo.itЗеланоДж.ZelanoG.

доктор медицины, доцент кафедры неврологии Католического университета Святого Сердца, научный директор Центра когнитивного образования и моторики.

 

MD, Assistant Professor, Department of Neuroscience, Catholic University of the Sacred Heart, Rome, Italy. Scientific Director of the Cognitive and Motor Education Center, London, UK.

giovanni.zelano@unicatt.itЦентр когнитивного образования и моторики, Великобритания. Ассоциация Европа, Италия.ВеликобританияAssociation «Europa», Aprilia, Italy. Cognitive and Motor Education Center, London, Uk.United KingdomЦентр когнитивного образования и моторики, Лондон, Великобритания. Католический университет Святого Сердца, Рим, Италия.ИталияDepartment of Neuroscience, Catholic University of the Sacred Heart, Rome, Italy. Cognitive and Motor Education Center, London, UK.Italy202118042021016064Copyright © Трушкова Н.В., Зелано Д., 20212021Трушкова Н.В., Зелано Д.Trushkova N.V., Zelano G.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.geriatr-news.com/jour/article/view/118Цель исследования

Цель исследования: проверить эффективность методики тренировок IntelligenceGym для улучшения когнитивных способностей у пожилых людей.

Материалы и методы

Материалы и методы: разработан оригинальный метод обучения и тренировок, который требует взаимодействия моторных и когнитивных функций. В исследование были включены 123 женщины и 89 мужчин в возрасте 68–76 лет, имеющие 23–25 баллов по краткой шкале оценки психического состояния (MMSE), автономность передвижения, отсутствие медицинских противопоказаний для участия в тренировках. Участники посещали занятия IntelligenceGym по часу два раза в неделю в течение 24 недель. Когнитивные способности оценивались до и после исследования, включая MMSE, Forward and Backward Digit Span Test, Rey’s Auditory Verbal Learning test (RAVLT), TMT-A, TMT-B. Моторные характеристики были проверены с помощью теста Time Up and Go (TUG).

Результаты

Результаты. Когнитивная оценка после тренировки IntelligenceGym показала статистически значимое улучшение по всем тестируемым шкалам.

Заключение

Заключение. Тренировки IntelligenceGym являются эффективным инструментом для улучшения когнитивных функций у пожилых людей с пограничным или умеренным когнитивным дефицитом.

Aim

Aim. The aim of our study was to verify the effectiveness of the innovative IntelligenceGym training in improving cognitive abilities in the elderly.

Material and methods

Material and methods. We developed an original training method that requires interaction between motor and cognitive functions. In our study 123 women and 89 men, aged 68–76 were examined. The inclusion criteria were Mini-Mental State Examination (MMSE) scores of 23 to 25 at inclusion, autonomy in walking, medical certification to participate in light physical activity. We have proposed to the participants to attend IntelligenceGym training one hour twice a week for 24 weeks. Cognitive performance was assessed before and after intervention included MMSE, Forward and Backward Digit Span Test, Rey’s Auditory Verbal Learning test (RAVLT), TMT-A, TMT-B. Moreover, motor performance was tested by using the Time Up and Go (TUG) test.

Results

Results.The cognitive assessment after IntelligenceGym training showed statistically significant improvement in all the scores tested (t-test performed). The results showed that participants of the IntelligenceGym training had particularly improved performance in Digit Span, MMSE and TMT-B tests and also improvements in motor TUG test.

Conclusion

Conclusion. These findings indicate that the IntelligenceGym training is an efficient tool to improve cognitive performance in older adults with borderline or mild cognitive deficiency.

когнитивная тренировканейропластичностьдвигательное обучениедвойная задачаcgnitive trainingneuroplasticitymotor learningdual taskoАвторы выражают признательность Меркушевой Людмиле Игоревне, к.м.н., гериатру, научному сотруднику лаборатории общей гериатрии и нейро-гериатрии ОСП РГНКЦ ФГАОУ ВО РНИМУ им. Н.И. Пирогова Минздрава России за помощь в переводе статьиReferencesLee Y., Kim J., Han E.S., Chae S., Ryu M., Ahn K.H., et al. Changes in physical activity and cognitive decline in older adults living in the community. Age (Omaha). 2015; 37(2)Lee Y., Kim J., Han E.S., Chae S., Ryu M., Ahn K.H., et al. Changes in physical activity and cognitive decline in older adults living in the community. Age (Omaha). 2015; 37(2)Cohen R.A., Marsiske M.M., Smith G.E. Neuropsychology of aging. In: Handbook of Clinical Neurology. Elsevier B.V. 2019; 149–80Cohen R.A., Marsiske M.M., Smith G.E. Neuropsychology of aging. In: Handbook of Clinical Neurology. Elsevier B.V. 2019; 149–80Ansay C., Manto M., Camut S., van Dun K., Mariën P., Habas C., et al. The CAM test: a novel tool to quantify the decline in vertical upper limb pointing movements with ageing. Aging Clin Exp Res. 2016 Apr 1; 28(2): 221–30Ansay C., Manto M., Camut S., van Dun K., Mariën P., Habas C., et al. The CAM test: a novel tool to quantify the decline in vertical upper limb pointing movements with ageing. Aging Clin Exp Res. 2016 Apr 1; 28(2): 221–30Seidler R.D., Bernard J.A., Burutolu T.B., Fling B.W., Gordon M.T., Gwin J.T., et al. Motor control and aging: Links to age-related brain structural, functional, and biochemical effects. Neurosci Biobehav Rev. 2010; 721–33Seidler R.D., Bernard J.A., Burutolu T.B., Fling B.W., Gordon M.T., Gwin J.T., et al. Motor control and aging: Links to age-related brain structural, functional, and biochemical effects. Neurosci Biobehav Rev. 2010; 721–33Seidler R.D., Alberts J.L., Stelmach G.E. Changes in multi-joint performance with age. Motor Control. 2002 Jan 1; 6(1): 19–31Seidler R.D., Alberts J.L., Stelmach G.E. Changes in multi-joint performance with age. Motor Control. 2002 Jan 1; 6(1): 19–31Buchman A.S., Boyle P.A., Wilson R.S., James B.D., Leurgans S.E., Arnold S.E., et al. Loneliness and the rate of motor decline in old age: The rush memory and aging project, a community-based cohort study. BMC Geriatr. 2010; 10: 77Buchman A.S., Boyle P.A., Wilson R.S., James B.D., Leurgans S.E., Arnold S.E., et al. Loneliness and the rate of motor decline in old age: The rush memory and aging project, a community-based cohort study. BMC Geriatr. 2010; 10: 77Cohen J.A., Verghese J. Gait and dementia. In: Handbook of Clinical Neurology. Elsevier B.V. 2019; 419–27Cohen J.A., Verghese J. Gait and dementia. In: Handbook of Clinical Neurology. Elsevier B.V. 2019; 419–27Wollesen B., Wildbredt A., Van Schooten K.S., Lim M.L., Delbaere K. The effects of cognitive-motor training interventions on executive functions in older people: A systematic review and meta-analysis. Eur Rev Aging Phys Act. 2020; 2; 17: 9Wollesen B., Wildbredt A., Van Schooten K.S., Lim M.L., Delbaere K. The effects of cognitive-motor training interventions on executive functions in older people: A systematic review and meta-analysis. Eur Rev Aging Phys Act. 2020; 2; 17: 9Hagovská M., Geriatrie ZO-Z für G. Relationships between balance control and cognitive functions, gait speed, and activities of daily living. Z Gerontol Geriatr. 2016 Jul; 49(5): 379–85Hagovská M., Geriatrie ZO-Z für G. Relationships between balance control and cognitive functions, gait speed, and activities of daily living. Z Gerontol Geriatr. 2016 Jul; 49(5): 379–85Bherer L. Cognitive plasticity in older adults: effects of cognitive training and physical exercise. Ann N Y Acad Sci. 2015 Mar 1; 1337(1): 1–6Bherer L. Cognitive plasticity in older adults: effects of cognitive training and physical exercise. Ann N Y Acad Sci. 2015 Mar 1; 1337(1): 1–6Marinelli L., Quartarone A., Hallett M., Frazzitta G., Ghilardi M.F. The many facets of motor learning and their relevance for Parkinson’s disease. Vol. 128, Clinical Neurophysiology. Elsevier Ireland Ltd; 2017; 1127–41Marinelli L., Quartarone A., Hallett M., Frazzitta G., Ghilardi M.F. The many facets of motor learning and their relevance for Parkinson’s disease. Vol. 128, Clinical Neurophysiology. Elsevier Ireland Ltd; 2017; 1127–41McGrath R.L., Kantak S.S. Reduced asymmetry in motor skill learning in left-handed compared to right-handed individuals. Hum Mov Sci. 2016 Feb 1; 45: 130–41McGrath R.L., Kantak S.S. Reduced asymmetry in motor skill learning in left-handed compared to right-handed individuals. Hum Mov Sci. 2016 Feb 1; 45: 130–41Sampaio-Baptista C., Sanders Z.-B., Johansen-Berg H. Structural Plasticity in Adulthood with Motor Learning and Stroke Rehabilitation. Annu Rev Neurosci. 2018 Jul 8; 41(1): 25–40Sampaio-Baptista C., Sanders Z.-B., Johansen-Berg H. Structural Plasticity in Adulthood with Motor Learning and Stroke Rehabilitation. Annu Rev Neurosci. 2018 Jul 8; 41(1): 25–40Voelcker-Rehage C., Willimczik K. Motor plasticity in a juggling task in older adults-a developmental study. Age Ageing. 2006 Jul 1; 35(4): 422–7Voelcker-Rehage C., Willimczik K. Motor plasticity in a juggling task in older adults-a developmental study. Age Ageing. 2006 Jul 1; 35(4): 422–7Driemeyer J., Boyke J., Gaser C., Büchel C., May A. Changes in gray matter induced by learning — Revisited. PLoS One. 2008 Jul 23; 3(7)Driemeyer J., Boyke J., Gaser C., Büchel C., May A. Changes in gray matter induced by learning — Revisited. PLoS One. 2008 Jul 23; 3(7)Altermann C.D.C., Martins A.S., Carpes F.P., Mello-Carpes P.B. Influence of mental practice and movement observation on motor memory, cognitive function and motor performance in the elderly. Braz J Phys Ther. 2014; 18(2): 201–9Altermann C.D.C., Martins A.S., Carpes F.P., Mello-Carpes P.B. Influence of mental practice and movement observation on motor memory, cognitive function and motor performance in the elderly. Braz J Phys Ther. 2014; 18(2): 201–9Shuggi I.M., Oh H., Wu H., Ayoub M.J., Moreno A., Shaw E.P., et al. Motor Performance, Mental Workload and Self-Efficacy Dynamics during Learning of Reaching Movements throughout Multiple Practice Sessions. Neuroscience. 2019 Dec 15; (423): 232–48Shuggi I.M., Oh H., Wu H., Ayoub M.J., Moreno A., Shaw E.P., et al. Motor Performance, Mental Workload and Self-Efficacy Dynamics during Learning of Reaching Movements throughout Multiple Practice Sessions. Neuroscience. 2019 Dec 15; (423): 232–48Raw R.K., Wilkie R.M., Allen R.J., Warburton M., Leonetti M., Williams J.H.G., et al. Skill acquisition as a function of age, hand and task difficulty: Interactions between cognition and action. PLoS One. 2019 Feb 1; 14(2)Raw R.K., Wilkie R.M., Allen R.J., Warburton M., Leonetti M., Williams J.H.G., et al. Skill acquisition as a function of age, hand and task difficulty: Interactions between cognition and action. PLoS One. 2019 Feb 1; 14(2)Kawasaki T., Tozawa R., Aramaki H. Effectiveness of using an unskilled model in action observation combined with motor imagery training for early motor learning in elderly people: a preliminary study. Somatosens Mot Res. 2018 Oct 2; 35(3–4): 204–11Kawasaki T., Tozawa R., Aramaki H. Effectiveness of using an unskilled model in action observation combined with motor imagery training for early motor learning in elderly people: a preliminary study. Somatosens Mot Res. 2018 Oct 2; 35(3–4): 204–11Ruge H., Schäfer T.A.J., Zwosta K., Mohr H., Wolfensteller U. Neural representation of newly instructed rule identities during early implementation trials. Elife. 2019 Nov 1(8)Ruge H., Schäfer T.A.J., Zwosta K., Mohr H., Wolfensteller U. Neural representation of newly instructed rule identities during early implementation trials. Elife. 2019 Nov 1(8)Cole M.W., Patrick L.M., Meiran N., Braver T.S. A role for proactive control in rapid instructed task learning. Acta Psychol (Amst). 2018 Mar 1; 184: 20–30Cole M.W., Patrick L.M., Meiran N., Braver T.S. A role for proactive control in rapid instructed task learning. Acta Psychol (Amst). 2018 Mar 1; 184: 20–30Sánchez-Cubillo I., Periáñez J.A., Adrover-Roig D., Rodríguez-Sánchez J.M., Ríos-Lago M., Tirapu J., et al. Construct validity of the Trail Making Test: Role of task-switching, working memory, inhibition/interference control, and visuomotor abilities. Vol. 15, Journal of the International Neuropsychological Society. Cambridge University Press; 2009; 438–50Sánchez-Cubillo I., Periáñez J.A., Adrover-Roig D., Rodríguez-Sánchez J.M., Ríos-Lago M., Tirapu J., et al. Construct validity of the Trail Making Test: Role of task-switching, working memory, inhibition/interference control, and visuomotor abilities. Vol. 15, Journal of the International Neuropsychological Society. Cambridge University Press; 2009; 438–50Zhang N., Du S.M., Zhang J.F., Ma G.S. Effects of dehydration and rehydration on cognitive performance and mood among male college students in Cangzhou, China: A self-controlled trial. Int J Environ Res Public Health. 2019 Jun 1; 16(11).Zhang N., Du S.M., Zhang J.F., Ma G.S. Effects of dehydration and rehydration on cognitive performance and mood among male college students in Cangzhou, China: A self-controlled trial. Int J Environ Res Public Health. 2019 Jun 1; 16(11).

The authors declare that there are no conflicts of interest present.